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June 18, 2013 Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of breast cancer, researchers from the University of Chicago report in the July 2013 issue of the journal Cancer Prevention Research . Some forms of stress exposure may be associated with an increased risk of certain types of aggressive breast cancer.
June 13, 2013 The ability to distinguish between odors declines steadily with age, but a new study shows that African-Americans have a much greater decrease in their sense of smell than Caucasians. This can have serious consequences.
June 11, 2013 The University of Chicago Medicine Comer Children’s Hospital has ranked among the best in four of 10 pediatric specialties, including in cancer, according to U.S. News & World Report’s latest list of the nation’s best children’s hospitals.
June 4, 2013 Minoli Perera, PharmD, PhD In the first genome-wide association study to focus on warfarin dose requirement in African-Americans, a multi-institutional team of researchers has identified a common genetic variation that can help physicians estimate the correct dose of the widely used blood-thinning drug warfarin. The discovery, reported online first in The Lancet , suggests that people of African ancestry who carry this variant — more than 40 percent of the patients enrolled in this study — need significantly less warfarin to obtain optimal benefits compared to those who lack this variant.
Inherited mutations in susceptibility genes are common in younger African American women with breast cancer
June 3, 2013 Jane Churpek, MD A high percentage of African-American women with breast cancer who were evaluated at a university cancer-risk clinic were found to carry inherited genetic mutations that increase their risk for breast cancer. The finding suggests that inherited mutations may be more common than anticipated in this understudied group and may partially explain why African-Americans more often develop early onset and “triple-negative” breast cancer, an aggressive and difficult-to-treat form of the disease.
May 28, 2013 Since the 1980s, doctors and patients have been encouraged to share decision making. Proponents argue that this approach promotes doctor-patient communication, enhances patient satisfaction, improves health outcomes, and even may lower cost.
May 24, 2013 Study authors Karthikeyan Veeraraghavalu, PhD, research associate, assistant professor (seated), and Sangram Sisodia, PhD, Thomas Reynolds Sr. Family Professor of Neurosciences, director of the Center for Molecular Neurobiology, Department of Neurobiology, led one of four teams from multiple institutions that tried — but were unable — to replicate a high-profile 2012 study describing remarkable results in treating mouse models for Alzheimer’s disease.
Jeffrey B. Matthews, MD, Dallas B.
May 22, 2013 Joseph J. Ceithaml, PhD, dean of students emeritus for the Pritzker School of Medicine and the Biological Sciences Division and professor emeritus of biochemistry and molecular biology at the University of Chicago, died on Saturday afternoon, May 11.