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Humans carry one to two lethal recessive mutations on average, study estimates

Humans carry one to two lethal recessive mutations on average, study estimates

April 9, 2015 Humans carry on average one to two mutations that, if inherited from both parents, can cause severe genetic disorders or death before reaching reproductive age, report scientists from the University of Chicago and Columbia University. The estimate is based on an analysis of the genealogy of an isolated founder population with more than 1,500 living descendants.

Charlene Sennett, MD, 1952-2015

Charlene Sennett, MD, 1952-2015

March 26, 2015 Charlene Sennett, MD, an associate professor of radiology at the University of Chicago Medicine and a highly respected clinical specialist in breast imaging, died at the medical center on March 23, 2015, after months of illness. She suffered a stroke while awaiting a heart transplant. Sennett, 62, was well known throughout the Chicago area as a thoughtful and talented clinician, dedicated educator and fierce advocate for her patients.

New analysis finds successes, gaps in community-based diabetes prevention programs

New analysis finds successes, gaps in community-based diabetes prevention programs

March 25, 2015 Lifestyle interventions designed to reduce the risk of developing type 2 diabetes can work well in group-based, community settings, conclude authors from the University of Chicago Medicine in a new report issued by the New York State Health Foundation (NYSHealth) on March 25, 2015. The report, supported by NYSHealth and the Robert Wood Johnson Foundation, evaluated evidence from 46 studies that used interventions such as diet, exercise or medication to prevent or delay diabetes in at-risk participants.

Polonsky reappointed as head of biological sciences, medical school and medical center at University of Chicago

Polonsky reappointed as head of biological sciences, medical school and medical center at University of Chicago

March 18, 2015 Kenneth S. Polonsky, MD, the Richard T.

UChicago symposium focuses on advances in cancer immunotherapies

UChicago symposium focuses on advances in cancer immunotherapies

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Plants’ defensive responses against herbivores have downstream effects on nearby ecosystems

Plants’ defensive responses against herbivores have downstream effects on nearby ecosystems

March 17, 2015 Chemical changes that occur in tree leaves after being attacked by insects and mammals can impact nearby streams, which rely on fallen plant material as a food source, report scientists from the University of Chicago Department of Ecology and Evolution. The study, published March 17 in the journal Proceedings of the Royal Society B , shows how interactions between terrestrial and aquatic ecosystems are an essential part of understanding ecological responses to climate change.

Blood pressure drug protects against symptoms of multiple sclerosis in animal models

Blood pressure drug protects against symptoms of multiple sclerosis in animal models

March 13, 2015 An FDA-approved drug for high blood pressure, guanabenz, prevents myelin loss and alleviates clinical symptoms of multiple sclerosis (MS) in animal models, according to a new study. The drug appears to enhance an innate cellular mechanism that protects myelin-producing cells against inflammatory stress.

Optogenetics without the genetics

Optogenetics without the genetics

March 12, 2015 Light can be used to activate normal, non-genetically modified neurons through the use of targeted gold nanoparticles, report scientists from the University of Chicago and the University of Illinois at Chicago. The new technique, described in the journal Neuron on March 12, represents a significant technological advance with potential advantages over current optogenetic methods, including possible use in the development of therapeutics toward diseases such as macular degeneration.

Ci3’s Game Changer Chicago Design Lab awarded $1 Million MacArthur Foundation Grant

Ci3’s Game Changer Chicago Design Lab awarded $1 Million MacArthur Foundation Grant

March 11, 2015 The John D. and Catherine T.

Pritzker School of Medicine program ranks 10th in latest survey

Pritzker School of Medicine program ranks 10th in latest survey

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